LONDON - Two men with prostate cancer that were at such an advanced stage they were considered inoperable, have dramatically recovered after being treated with an experimental drug, the Sunday Times reported.
Both are cancer-free and have returned to normal life, the newspaper said.
It said the two men, Rodger Nelson and Fructuoso Solano-Revuelta, took part in US trials of a drug called Ipilimumab.
Researchers were so excited by the mens recovery that they released details before completion of the tests, which involved 108 men in all, the paper reported.
Eugene Kwon, who led the trial at the Mayo Clinic in Minnesota, said the two patients were not expected to survive, but we were startled to see responses that far exceeded expectations.
The patients received traditional hormone therapy to remove testosterone, which fuels prostate cancer. They then had one dose of Ipilimumab, an antibody that boosts the immune systems response.
Both patients saw their prostate specific antigen (PSA) levels drop to the point where they could have surgery.
But when the surgeons made their incisions, urologist Michael Blute said: The tumours had shrunk dramatically. I had a hard time finding the cancer.
John Neate of the Prostate Cancer Charity in the UK told the Sunday Times: If these early and small-scale results are replicated in larger trials, this represents a potentially very exciting development.