People who could benefit from insulin are fearful of injections, so they delayed treatment by 5-10 ten years, placing themselves at risk of serious complications.
Exubera (manufactured by Pfizer) can improve blood sugar level with fewer or no painful injections.
Read more on The Diabetes Blog [Pfizer Receives FDA Approval for Exubera - First Inhalable Insulin for Controlling Type-1 and Type-2 Diabetes]
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Insulin Inhaler Exubera Rejected by National Institute for Health and Clinical Excellence for CostApril 24th, 2006 Insulin that can be inhaled rather than injected has been rejected by NHS advisers on grounds of cost. The inhaled insulin “Exubera” is the first non-injected option for insulin therapy since the discovery of the treatment for diabetes in the 1920s.
Technosphere Insulin Over Other Treatment RegimensMarch 11th, 2006 Diabetes and cancer treatments developer MannKind has initiated patient enrollment in two pivotal 12-month phase III clinical trials of its Technosphere Insulin in patients with type 1 and type 2 diabetes. The main objective of these studies is to evaluate the efficacy of Technosphere Insulin (TI) by assessing changes both in HbA1c levels as well as in blood glucose levels after a standardized meal.
Extended-Release Type 2 Diabetes Drug, ACTOplus met, Submitted for FDA ApprovalApril 10th, 2006 ACTOplus met, a New Drug Application for an extended-release version of its type 2 diabetes drug would allow for once-daily dosing was submitted by Takeda Pharmaceutical Co.’s (4502.TO) U.S. Extended-release metformin, one of the active ingredients in ACTOplus met XR, was developed by Andrx Corp.
Drug Cocktail May Reverse DiabetesApril 24th, 2006 Cocktail of the two drugs, the anti-CD3 antibody and proinsulin peptide, developed by scientistsin California, can reverse Type 1 diabetes, which usually starts in childhood and occurs when the immune system turns on itself and attacks the insulin-producing cells of the pancreas. This method which has to date only been tested on animals but each of its constituents is already being tested individually in human clinical trials can give potential end to the daily routine of insulin injections and rigid dietary restrictions suffered by millions throughout the world.
Smoking May Increase Insulin Resistance (Diabetes Type 2 Risk) At Cellular LevelApril 10th, 2006 Secondhand smoking may increase insulin resistance at the cellular level, which would contribute to diabetes. For the first time, a study has linked secondhand smoke with the development of diabetes, according to an article written by a Birmingham researcher and published Friday in the British Medical Journal.
New Drugs Slows The Progress of Juvenile DiabetesMarch 11th, 2006 An international research led by New York’s Columbia University shows promise of slowing the progress of Juvenile diabetes, also known as Type 1 diabetes. The researchers say their effort includes using drugs normally given to organ-transplant patients.
Freedom From Insulin Injections Closer To RealityMarch 27th, 2006 Thanks to University of Calgary researchers who are developing the first bioreactor procedures to grow pancreatic cells in their laboratory. This opens the door to the possibility of providing a steady supply of insulin-producing cells that can be transplanted into patients affected by this serious disease.
New study counter-attacks the immune response that causes insulin-dependent diabetes August 26th, 2008 Good news for the patients suffering from (insulin-dependent) Type 1 Diabetes. As now doctors of Masachusetts has discovered a new way to cure Type I Diabetes by isolating and killing the defective immune system cells that wipe out insulin-producing cells in the pancreas.