New Patch To Prevent Traveler’s Diarrhea


Researchers are likely to develop a new vaccine to prevent traveler’s diarrhea. Researchers testing the experimental diarrhea vaccine found that the skin patches reduced the likelihood of contracting traveler’s diarrhea among people especially to those who go to the high-risk areas like Mexico. It can be added that 27 million travelers and 210 million children each year are hit by diarrhea, often from eating contaminated food or drinking contaminated beverages, that lasts about four to five day. The study was published in the magazine The Lancet .

Diarrhea vaccine bacteria are a leading cause of traveler’s diarrhea. When these bacteria colonize the small intestine, they secrete toxins that cause diarrhea. The toxin most commonly linked to diarrhea from this E. coli is called heat-labile enterotoxin (LT).

This phase II clinical trial, compared the effectiveness of the vaccine patch in a group of 170 healthy adults planning to travel to Mexico and Guatemala. The average length of stay was 12 days.

Researchers randomly assigned 59 participants to receive the vaccine patch; 111 received a placebo patch. One patch was placed on the participants’ upper arm three weeks prior to departure; another patch was placed on the alternate arm one week before traveling. The patch was worn for six hours after application and then discarded. The result showed 22% of those who got the placebo patch developed diarrhea compared with 15% of those who got the vaccine patch.

Source: WebMD

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