HIV Scientists Make a Major Discovery Towards Treatment and Cure艾滋病毒的科学家作出重大的发现对治疗与防治
In a move that has stunned HIV experts, German scientists reported yesterday that they had engineered an enzyme that attacked the DNA of the HIV virus, and cut it out of the infected cell.在这一举措已震惊艾滋病毒专家，德国科学家昨天报道说，他们设计的一种酶攻击的DNA艾滋病毒，减少它的受感染的细胞。
Until now, HIV research had focused on improving ways to stop infection spreading, thereby postponing the onset of AIDS, when opportunistic infections overwhelm the body’s damaged immune system.直至目前为止，艾滋病毒研究的重点是改进的方法，阻止感染扩散，从而推迟发病的艾滋病，当机会性感染，压倒身体的免疫系统受损。
Other areas of research, more hypothetically, are seeking a vaccine to prevent infections taking hold in the first place.其他的研究领域，更多的假设，现正寻求一种疫苗，以防止感染把握摆在首位。 Rooting out established infections had been thought of as next to impossible.铲除设立的感染已思想作为明年是不可能的。
Cutting HIV out of infected cells had been dismissed as a distant dream because the virus is so good at hiding itself.切割出的艾滋病毒感染的细胞已被视为是一个遥远的梦想，因为病毒是如此善于隐藏自己。 As a retrovirus, HIV splices itself into the host cell’s DNA — meaning it is inextricably linked to the person it has infected.作为一个逆转录病毒，艾滋病毒接合本身进入宿主细胞的DNA -的含义，这是有着千丝万缕的联系，该人已受到感染。
The infected cell can remain in a latent state, when it is all but undetectable by the body’s defence mechanisms, or it can become active.受感染的细胞可以留在一种潜在的状态，当它所有，但undetectable由身体的防御机制，或者它可以成为活跃。 When activated, the infected cell turns into a factory for making more viral copies, killing the cell in the process.一旦启动，受感染的细胞变成了工厂，为使更多的病毒副本，造成细胞在这个过程中。 The new copies go out to infect other cells.新的副本，走出去感染其他细胞。
What makes HIV so pernicious is that it targets the immune cells that co-ordinate the body’s fight against invaders.什么使艾滋病毒，使有害的是，它的目标是免疫细胞，负责统筹机构的打击侵略者。
While existing anti-retroviral drugs are effective at stopping the virus from replicating, they cannot root out the viral DNA, meaning that replication takes off again if patients try coming off the medications.而现有的抗逆转录病毒药物是有效的阻止病毒的复制，却不能治本出病毒DNA ，这意味着复制起飞再次如果病人尝试未来小康的药物。
In the German experiments, the enzyme recognised sections of infected cell DNA as belonging to HIV, and cut it out.在德国的实验中，酶认可部分受感染的细胞DNA属于艾滋病毒，并削减出来。 The enzyme, Tre recombinase, eliminated the virus from the infected cells in about three months.酶， tre重组，淘汰了病毒从感染的细胞在3个月左右。
Filed under提起下 AIDS艾滋病 , ， Health健康 |
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